A new review in the Journal of Translational Medicine consolidates how the replication-initiation protein ORC1 safeguards ...

Eukaryotic DNA replication is initiated at multiple origins through a tightly regulated sequence of events: origin licensing, helicase activation and assembly of the replisome. The replicative ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

HUSTON, TX, UNITED STATES, September 2, 2026 /EINPresswire.com/ — Proliferating Cell Nuclear Antigen (PCNA) is a core protein governing DNA replication, damage ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...